Enter one of he following codes at the indicated screen.

Note: Some of the codes may need to be used multiple times before they have any effect. Also, enabling codes by not allow achievements to be unlocked.

Go to a S.H.E.I.L.D. save zone and select "Change Team". Delete all selected characters by pressing X. Once all of your team slots are empty, press Down, Left(2), Up, Right, Up, Down, Left, Start. A sound will confirm correct code entry. Note: This code may also be enabled at the main menu.

Go to a S.H.E.I.L.D. save zone and select "Change Team". Delete all selected characters by pressing X. Once all of your team slots are empty, press Left(2), Right(2), Up, Down, Up, Down, Start. A sound will confirm correct code entry. Note: This code may also be enabled at the main menu.

Complete each of the following achievements below to get the allotted gamerscore.

There are a total of 7 playable characters which can be unlocked after performing certain ingame criteria.

Certain character combinations unlock special boosts.

Gain between two and four levels with a character. Alternately, defeat 30 enemies with a character to unlock his or her second costume. Defeat 175 enemies with a character to unlock his or her second costume.

Complete the Combat Training challenge for a character. Alternately, get a "Bronze" rank in a character's Comic Mission to unlock his or her fourth costume.

The following 12 achievements require the Xbox 360 exclusive expansion.

Additionally, there are 25 secret achievements.

Successfully complete the game under the normal difficulty setting.

Play the Galactus Boss battle. When he slams his fists and swipes at you, it does not hurt at all and you will get back up immediately. You are up on a ledge and his Punishers do not stop respawning. You can just grab and throw them off in either direction. To avoid being caught in his hand and button tapping, go on the left side of the screen on that corner.

Use the following trick to make a hard to kill team. Make a team consisting of Wolverine, Blade, Ghost Rider, and Luke Cage (the Bad To the Bone team). The team bonus will be that 5% of all damage will regained as health. Also, all these characters have a way to regenerate health. Equip he following outfits. For Wolverine, Astonishing, Max Out Health Regen and Defense. For Blade, Ultimate, Max Out Health Regen and Defense. For Luke Cage, New Avengers, Max out Health Regen and Defense. For Ghost Rider, Original, Max out Resurrect Ally and Defense. It is also recommended that Ghost Rider be equipped with The Heart of Mephisto (10% of attack damage turned into health) or a similar item because he is the only character without a Health Regen. Equip other characters with gear that increases defense or dodging capabilities. Not only will your team be difficult to hurt, but they will be absorbing and regenerating most of the damage they take. If a teammate dies, Ghost Rider will have a 50% chance of resurrecting them. Note that Ghost Rider is the weak point. He does not regenerate, and if he dies resurrection is lost. Also, Wolverine will regenerate the fastest because he has an inherit ability to regenerate in addition to the suit's bonus.

When lighting the candles in Mephisto's Realm, there is an area where you are meant to throw the demon jumpers into the fire to lower the pedestal. If you stand in by the edges of the level where the jumpers respawn, you can kill as many as desired. Try this as Spider-Man or any rapid fire projectile user. The enemies constantly drop money and energy refills. If one walks too far away, hopefully your teammates will chase after them and you can use the momentum move to wipe them out. Do this for easy experience and money.

When picking up character specific items, such as "Iron Man's Coil", it is described as doing +3 Damage and +3 Rocket Uppercut. This is not +3 to damage for the hit; it means that it adds three dots in the Powers area. With this single item you can go from 129 Damage to 289 Damage. Character specific gear are thus very valuable.

Do not be afraid of the hard difficulty setting. When you start a game under hard mode, you can load your characters from a previously saved game. For example, if you have a level 50 Wolverine from normal mode, you can start the game with him and all his powers, gear, and costumes that you have gained. It also adds five more dots to level up your powers with. If you have one maxed out in normal mode, there is even more room for improvement.

To complete all the Comic missions easily and unlock Silver Surfer and get gold at the same time, wait and play all the missions at the end of the game when your characters have leveled up and have decent powers. If some are still to difficult to complete, do some Versus mode missions with those characters to level them up, or to pick up some Shield Tokens to add to their costume.

When you get to the end of the mission to battle Ultimo, run back to the door you came in. Ultimo is so big he cannot pass the edge of the room he is in. You can just sit back and hit him with your ranged attacks. Then when needed, fly in and collect the health and energy vials he drops.

After the third level, go to Iron Man's lab and talk to Spider-Man. He will say "The only thing that could make this worse is if Earth was blown up to make an intergalactic highway".

During the missions is Asgard you may talk to Weasle after completing one of the two missions available. Weasle will be in the Hall of Heroes. After he talks to you, talk to him by pressing X. When you ask him about the Ex mansion, the subtitle reads "Makes me wish I was a mutant. They've got everything here - tennis courts, a pool, and a subbasement full of hi-tech gear" however the voice artist clearly says "They've got everything there", which would be the correct way to say it.